For pseudo differential input:
V+ connected to Vsignal (Assuming varies from 0 - VDD)
V - connected to VDD/2
Your common mode will be changing from VDD/4 to VDD*3/4.
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For fully differential input
V+ connected to Vcom +Vsignal
V- connected to Vcom - Vsignal
Your common mode voltage will always be Vcom
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They will not have the same common mode voltage if you vary the input.