1. You can refer to Cadence document for noise format. As far as I remember, it is a two-column format. the first column is frequency and the second column is noise spectral density.
2. typically VCO will have its own regulator. The regulator reduces interference from other blocks that share the same power supply.
3. You can add a noise signal to your power supply (say, a sinusoidal), run transient sim and do FFT to check the Spur effect.
V/sqrt(Hz) is used in the noise profile. You can test it with a simple testbench that includes only a voltage source with the noise profile and run a noise simulation. I am not exactly sure which Cadence document describes the noise profile, but I guess you should be able to find that in User manual of Virtuso or similar documents. Good luck.
Sorry I made a mistake in the noise file. I came across one of my testbenches today and found that the unit for noise should be V^2/Hz rather than V/sqrt(Hz). You can find that out also from Virtuso Cadence Circuit Simulator RF Analysis User Guide.